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Xanthohumol

A representation of Xanthohumol
Two green herbal pills isolated on white background. Close-up macro view

Xanthohumol is a plant substance that belongs to the polyphenols and is only found in hops. Hops are primarily known as an ingredient in beer, but also as a medicinal plant with a calming effect. But what does xanthohumol have to do with dogs and what advantages and disadvantages does it have for the health of your four-legged friend? In this article, you can find out more about this interesting ingredient and its possible applications.

What is xanthohumol?

Xanthohumol is a yellow-colored substance that is formed in the lupulin glands of the hop plant. It belongs to the chalcones, a subgroup of polyphenols, which are also found in other plants such as red clover and soy. Polyphenols are secondary plant substances that can have various bioactive properties, such as antioxidant, anti-inflammatory or hormone-regulating.

Xanthohumol was discovered as early as 1913, but its potential as a chemopreventive agent has only been researched in recent years. This means that it can inhibit or slow down the development and growth of cancer cells. It has also been shown to protect the nerve cells of the brain from oxidative stress and thus prevent neurodegenerative diseases such as Alzheimer's or Parkinson's.

How does xanthohumol affect dogs?

The effect of xanthohumol on dogs has not yet been sufficiently researched, but there are some indications from animal and cell studies that point to positive effects. For example, a study on mice found that xanthohumol strengthens the immune system and promotes the formation of antibodies. In another study on rats, xanthohumol was observed to improve liver function and reduce fat accumulation.

For dogs, xanthohumol could therefore play a role in the prevention or treatment of various diseases, such as

  • Cancer: xanthohumol can protect DNA from damage, regulate cell division and trigger the death of cancer cells. It can also enhance the effects of chemotherapy or radiation or alleviate their side effects.
  • Inflammation: Xanthohumol can inhibit the release of pro-inflammatory messengers such as TNF-alpha or IL-6 and thus reduce inflammatory reactions in the body. It can also suppress the formation of prostaglandins, which are responsible for pain and fever.
  • Ageing process: Xanthohumol can neutralize free radicals that can lead to cell damage and ageing. It can also increase the activity of enzymes responsible for cell repair and protection against oxidative stress.
  • Brain health: Xanthohumol can promote blood flow to the brain and stimulate the production of nerve growth factors. It can also improve the function of neurotransmitters such as dopamine or serotonin and thus influence mood and learning.

What are the advantages and disadvantages of xanthohumol for dogs?

As with any botanical, there are pros and cons to xanthohumol that you should consider before giving it to your dog. Here are some points to weigh up:

  • Pros: Xanthohumol has a wide range of health benefits that can help your dog live longer and better. It can reduce the risk of various diseases or alleviate their symptoms. It also has a calming effect that can help your dog with stress or anxiety.
  • Disadvantages: Xanthohumol has not yet been adequately tested for its safety and dosage for dogs. It can also potentially have side effects or interactions with other medications or supplements. It can also affect your dog's hormone balance, which can be particularly problematic in pregnant or lactating bitches.

How can I give xanthohumol to my dog?

Xanthohumol is available in various forms, such as powder, capsules or drops. You can give it directly into your dog's mouth or mix it into their food. The dosage depends on various factors, such as your dog's weight, age and state of health. There are no general recommendations yet for the optimal dose of xanthohumol for dogs, so you should always follow the manufacturer's instructions or ask a vet for advice.

A possible rule of thumb is that you should not give your dog more than 0.5 mg of xanthohumol per kilogram of body weight per day. This corresponds to about 10 mg for a 20 kg dog. However, this dose should not be exceeded, as otherwise undesirable effects may occur.

 

Xanthohumol is a promising plant substance that can bring many benefits for your dog's health and well-being. It has antioxidant, anti-inflammatory and anti-cancer effects and can also protect the brain and immune system. However, it has not yet been sufficiently researched and may also have side effects or interactions. Therefore, you should always inform yourself well and dose carefully before giving xanthohumol to your dog.

Learn even more about Xanthohumol

If you notice any signs of hypersensitivity or poisoning in your dog, you should see your vet immediately. We are not a substitute for a vet, but we try to be as accurate as possible. Every dog reacts differently and we recommend you get a second opinion or consult your vet if in doubt.

Stay healthy and take good care of your four-legged friend!😊