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TSH stimulation test

The TSH stimulation test is an examination performed on dogs to check the function of the thyroid gland. The thyroid gland is an organ that produces hormones that affect metabolism and other bodily functions. If the thyroid gland produces too little or too much hormone, this can lead to various health problems.

What is TSH?

TSH stands for thyrotropin or thyrotropic hormone. It is a hormone that is secreted by the pituitary gland and stimulates the thyroid gland to produce the hormones thyroxine (T4) and triiodothyronine (T3). These hormones are responsible for regulating metabolism, body temperature, heartbeat, growth and development.

Why is a TSH stimulation test carried out?

A TSH stimulation test is performed to determine whether a dog's thyroid gland is functioning normally or whether it is under- or overactive. An underactive thyroid gland (hypothyroidism) can lead to symptoms such as weight gain, hair loss, lethargy, sensitivity to cold and skin problems. An overactive thyroid (hyperthyroidism) can lead to symptoms such as weight loss, nervousness, palpitations, diarrhea and vomiting.

How is a TSH stimulation test carried out?

A TSH stimulation test is usually carried out in a veterinary clinic or laboratory. The dog must be fasting, i.e. it must not eat or drink anything 12 hours before the test. The vet takes a blood sample from the dog and measures the T4 level in the blood. He then injects a dose of TSH into the dog's vein and takes a second blood sample 4 to 6 hours later. He then measures the T4 level in the blood again.

How are the results interpreted?

The results of the TSH stimulation test show how the dog's thyroid gland reacts to the TSH. If the T4 level in the blood rises significantly after the TSH injection, this means that the thyroid gland is functioning normally. If the T4 level in the blood does not rise or rises only slightly after the TSH injection, this means that the thyroid gland is underactive. If the T4 level in the blood is very high before and after the TSH injection, it means that the thyroid gland is overactive.

What are the benefits and risks of a TSH stimulation test?

The benefit of a TSH stimulation test is that it provides an accurate diagnosis of thyroid function. It can help to rule out other causes of similar symptoms and determine the correct treatment for the dog.

The disadvantage of a TSH stimulation test is that it is relatively expensive and time consuming. It requires two blood draws and a waiting time of several hours between samples. In addition, the dog may have an allergic reaction to the injected TSH or the TSH may damage the thyroid gland.

The TSH stimulation test is an important test for assessing thyroid function in dogs. It can help to detect hypo- or hyperthyroidism and treat it accordingly. However, the test should only be carried out by a qualified vet who can interpret the results correctly.


The authors assume that a veterinarian should be consulted if an animal is ill and that medication should only be taken after consultation with a doctor or pharmacist. Only an individual examination can lead to a diagnosis and treatment decision.

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