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Addison's disease

A representation of Addison's disease

Addison's disease, also known as hypoadrenocorticism, is a rare hormonal disorder that affects the adrenal glands. The adrenal glands are small organs located above the kidneys that produce important hormones that regulate metabolism, blood pressure, water and electrolyte balance, and the body's stress response. If the adrenal glands do not produce enough of these hormones, an imbalance occurs which can lead to various symptoms.

Causes of Addison's disease in dogs

Addison's disease can have several causes, but the most common is an autoimmune disease in which the immune system attacks and destroys the adrenal glands. Other possible causes are:

  • Infections or tumors that damage the adrenal glands
  • Drugs that inhibit or interrupt the hormone production of the adrenal glands
  • Genetic factors that increase susceptibility to the disease
  • Trauma or surgery that affects the blood supply to the adrenal glands

Symptoms of Addison's disease in dogs

The symptoms of Addison's disease are often non-specific and variable, which can make diagnosis difficult. Some of the most common symptoms are:

The symptoms can develop gradually or occur suddenly, especially in stressful situations. In severe cases, a life-threatening Addisonian crisis may occur, requiring an immediate visit to the vet.

Diagnosis of Addison's disease in dogs

To diagnose Addison's disease in dogs, the vet will need to take a thorough medical history and perform a physical examination. Blood and urine tests are also performed to measure adrenal hormone levels and rule out other diseases. The most important test is the ACTH stimulation test, in which the dog is injected with a synthetic hormone designed to stimulate the adrenal glands. If the adrenal glands are functioning normally, they should then produce more hormones. If they do not respond or respond only slightly, this indicates Addison's disease.

Treatment of Addison's disease in dogs

The treatment for Addison's disease in dogs is to replace the missing hormones and restore the body's balance. To do this, the dog is administered medication, which can be given either orally or by injection. The dosage must be adjusted individually and checked regularly. The medication must be given for life to prevent a relapse.

In addition to hormone therapy, the dog must also be supplied with fluids and electrolytes to compensate for fluid loss. This can be given orally or intravenously, depending on the severity of the symptoms. The dog should also receive a balanced diet and avoid or minimize stressful situations.

Prognosis of Addison's disease in dogs

The prognosis of Addison's disease in dogs is good if it is recognized and treated early. Most dogs can lead a normal life with appropriate therapy. However, they need regular visits to the vet to monitor their hormone levels and adjust their medication. They also need to be treated quickly in emergencies to avoid an Addisonian crisis.

Addison's disease is a serious condition that can endanger a dog's life. If you notice signs of Addison's disease in your dog, you should take him to the vet as soon as possible to get a diagnosis and treatment. With the right care and support, you can help your dog cope with this disease and have a good quality of life.


The authors assume that a veterinarian should be consulted if an animal is ill and that medication should only be taken after consultation with a doctor or pharmacist. Only an individual examination can lead to a diagnosis and treatment decision.

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